Too true, but be careful that "independant thought" does not become the dogma. (Political opposition parties are masters of the negative argument and where does that get us) One must come to a conclusion at some point and often, good enough is good enough. That goes for hypotheses/scientific theories too.
I'm not trying to personally attack here, but am going to call you on the below three comments you've made as being inconsistent.
I certainly don't take it personally and hope you don't take the following personally, either. There is no inconsistency here. What we have is a misunderstanding on what constitutes evidence.
I say that evidence and explanation has been provided on both points of protein denaturation and renaturation and on yeast attack on hot break and lipid release.
On yeast attack: A track to pursue was given and I said I would endeavour to seek out that information and read it for myself. As far as renaturation goes, examples were given about proteins in general. You recognise this yourself. Hence, it's a hypothesis that denatured proteins in wort may renature under certain conditions. There is no evidence for this.
You intimate that proof is not important. You quote that absolute proof is not particularly scientific. You quote that all science can do is reject or falsify hypotheses.
Proof is something that mathematicians do. Not scientists.
You state that if there is so much evidence as to why it is best practice (removal of hot break) then why is it so difficult to produce, yet when evidence and explanation is produced you reject it as not being specific enough.
That's right. I would like to see specific explanations of HOW hb affects flavour, stability, etc. I think that is reasonable to ask someone who has access to information not easily found, and is an ardent advocate for separating hb. If the studies haven't been done then it's simply a matter of MHB saying "I don't know how it's a problem, I just know that it is".
You then confirm that enzymes breaking down protein coagulates and redissolving of denatured proteins are hypotheses, but state that there is no evidence for this? Again I beg to differ that there is no evidence. Infact if you accept that they are hypotheses then given your above beliefs, there must be evidence.
Good hypotheses are based on evidence. For example, enzymes break down proteins, therefore enzymes may break down protein-polyphenol complexes in wort. This would then have to be studied to confirm if this is indeed the case. According to MHB, Kunze discusses this. I would like to read it for myself. Another example of an evidence based hypothesis is that proteins renature under certain conditions so they may renature in wort with a change in pH. This would have to be confirmed through experiment. If someone has confirmed this then I would be interested to read about it.
MHB and myself have provided evidence and explanation (as you required above) for the hypotheses (MHB provided a source which has the evidence. You provided a possible explanation). Surely given your beliefs and scientific background, it is down to you to come up with some evidence that these hypotheses are misguided or incorrect. (The hypotheses aren't misguided. I would just like to read the studies that confirm them first hand) Or at least do some research and quote to us some inaccuracies.
I am happy to say that I am wrong about the hypothesis if stronger evidence (stronger than none?) is found that debunks it. I am interested though as to why you seem to struggle against reasonable production of evidence again and again, when you seem to whole heartedly embrace the idea that Hot break should be kept out of the fermenter. It may well be the duality of man perhaps?
Again, I can't say this enough.
MHB provided a source of evidence that i would like to read. I understand his reluctance to produce it given that we are all busy people. You have provided a possible explanation that has not been studied directly. As MHB states, that is probably because there is no value in understanding HOW it works and WHY it's detrimental. Big beer is content to know that it IS bad and that's where the study ends. I still find this surprising because I could imagine they could benefit from knowing the mechanism but that's just me.
Can you not see why MHB may have gotten frustrated?
No