It tastes a bit more yeastier out the fermenter - generally.
A simple APA can almost work out predictably throughout the fermenting bit (ooh, fruity, turn the fridge down... - ooh, sharp - pyruvic acid, it's just starting...), whereas a more complex grain bill or a very scientific/clean lager can be a little less predictable. I really wasn't expecting what I got from the Korbinier clone I made last year based on the treacle that oozed out of the fermenter..
Remember to taste, don't spit it back in...