The rate of isomerization drops off very quickly lower than 100.. but continues down to about 75 before it becomes basically insignificant. You have to remember though, that you have a long time at those sub boiling but still high temperatures. So what you miss out on in rate of change, you make up for in time for change to happen.
I have done a few experiments on this, both sensory and measuring IBUs in the lab; and my results suggest that adding Pellet hops loose into a cube (racked after whirlpool approx 90-95C) gives you a bitter quotient equivalent to adding the same amount of hops at 20-25 minutes from the end of the boil. Put em in a hop bag or tea ball, use flower hops or both... its going to be less, maybe significantly less. If you use a lot of IBUs worth of cube hops.. I suspect the utilization will also drop off. I have and know that others have tried; an all cube hop beer - calculated at 25mins equivalent... and the beer was under bitter. So if you were going to try that (it gives amazing flavour and aroma...) I would be thinking more along the lines of equal to 15mins in the boil.
I add pretty much any hop that isn't a straight bittering addition into the cube - this cuts the amount of bittering hop I need to use and gives really fantastic hop flavour plus a deep (although not intense) kettle hop aroma. IMO, you don't get the more volatile/resinous/perfumey aromas that you can get from a whirpool or hopback addition... the prolonged heat changes those compounds.
I don't think you can replicate kettle hopping with dry hopping - they are different. So when I want that hopback/whirlpool type aroma, I find that a hop tea, added at 2/3rds attenuation does the trick. I add the hops to a coffee plunger, give them 1 minute contact with 500ml of boiling water - plunge and tip the water into the fermenter - then I add another 500ml of boiling water and give them 3-5 mins contact, plunge and tip.
The reasons for this method are - To emulate a hopback via
Actual contact with hot liquid
But short contact followed very quickly by rapid cooling.
So the Terpene fractions of the hop oils have a chance to interact with the heat and oxidise a bit, but the hydrocarbons have minimal (but some) chance to volatilize.
I add at 2/3rds through fermentation so that neither contact with the yeast nor C02 stripping has too much of a chance to drive off the aroma I went to so much trouble to make... but so there is a little of both of those things during the last part of active fermentation... which tends to smooth out any harsh or grassy characteristics. You could add the tea at the very end of fermentation.. but I would go for a longer steep time on the hops to smooth it out a bit, this would mean more hops to get the same level of aroma compounds in the beer. Or just cold conditioning the beer for an extra week or two.
Thats how I do it anyway
TB