If you do end up with an infection, it's not going to be due to a seal failure on the lid. It's not like bacteria will somehow crawl in through an air gap, especially if there is only a tiny leak due to pressure inside. Flat beer would be a disappointment, but it's probably a better option than a whole bottle of CO2 lost due to a slow leak.Crakkers said:One problem you might encounter is the keg not sealing properly as you don't have the gas setup yet to pressurise the keg.
If the lid doesn't seal properly, any CO2 produced by the secondary fermentation could leak out, leaving you with a flat and potentially infected beer if any nasties find their way inside.
If your lids are not sealing properly, pay attention to the lid alignment, lube the o-ring and if necessary replace the o-ring with a new one. If your kegs are so beaten up you can't get the lids to seal even with the above, then perhaps it's time to retire those kegs, or at least re-purpose them.