Patience (up to a point anyway) can make a big difference to your brewing, BrewBright is a "Process Aid" it just makes something that will happen naturally happen faster/easier, you don't have to use it.
That said it does make whirlpooling and trub separation quicker and easier and helps you get more wort out of your kettle and improves the shelf life of your beer.
For me its a trade off, and for the relatively small cost I'm happy to get the time back that I would otherwise spend standing around waiting for things to happen naturally, not a right wrong answer - just a choice between trade-offs.
If you are boiling kit or extract beers BrewBright will help any hot break that forms to settle better, out to ridiculously long boils (8+ Hours) hot break will continue to form, protein will continue to condense and form flock, the most harmful high molecular weight protein will condense first and as time passes more and more of the smaller proteins will break. at some point you would start removing protein that we actually want in the beer (head and mouth feel).
At about 3 hours all of the really high molecular weight protein will be gone, most of the mid range and about half of the lower weight potentially beneficial protein will have broken.
Where I'm heading with this is that in spite of being a bit of an anti hot break Nazi, well made extract should have had most of the high MW protein removed during its manufacture, so you would need to be a lot less concerned about break material than would a brewer starting with the full concentration of protein that we find in a new wort.
Naturally if you are working with the cheapest crap on the market its liable to be made from enzyme extracted raw animal feed grade barley (and any other cheap grain) and be chockers with protein and other crap we don't want in beer - I could tell you about a sample I got once... (well it might have been OK for making biscuits but never for brewing), you would have lots of other problems besides protein, but BrewBright would help with that at least.
Mark