Making a big Imperial Stout on Friday at OG 1.094 and thought I'd make up a starter from 2 x Wyeast 1028 (super fresh March 24th). Before I went to work this morning I gave them a smack and left them till I got home. When I did one had inflated like a balloon whilst the other was only about half the size, I made the starter, pitched and noticed that one half of the nutrients hadn't opened up. Is this going to cause any issues, starter was 1.7 litres as per Mr Malty?