One of the points will be the size of the beer line that you use. If you find that the pressure you need to use to dispense is too high, then beer lines with a greater internal diameter will restrict the flow of the beer less and let you use lower pressures - a big help for long runs. Websites like (http://ceisites.com/balance.html) describe the "formula" for calculating, although no doubt there will still be a healthy amount of experimentation. I did try the figures off of the website mentioned and found that the "minimum" resistance values were closer (for the 3/16" tubing I had). I ended up testing a long length of the hose and raising the pressure till it would pour properly, thus determining the resistance for myself, cut the tube a bit too long and cut it back bit by bit to arrive at the correct length.
As an idea, a bit over 2m (close to 2.5 I think) of 4mm ID tubing is around the mark in my bar fridge with font setup (for a more highly carbonated beer style), however with 6 or 7mm tubing you should easily get the beet upstairs without having to raise the pressure on the keg.